Isolation and Characterization of Two Cucurbitane Type Triterpenoid Glycocide from 1-Butanol Soluble Part of Momordica charantia Fruit Pulp Juice

M Shakhawoat Hossain, M Kamrul Hasan, M Shoeb, M I R Mamun, N Nahar, M Mosihuzzaman

Abstract


Momordica charantia is a member of the Cucurbitaceae family having diverse biological activities. Two cucurbitane type triterpene glycoside have been isolated from 1-butanol soluble part of clear juice of M. charantia fruit pulp through column chromatography and HPLC. The isolated compounds were characterized as compound MC1 (3β, 7-O-β-glucopyranosyl-25-methoxy cucurbita –5-en-19-al) and compound MC2 (5β, 19-epoxy- 3- O-glucopyranosyl-25 methoxy cucurbita-6, 23-dien) with the help of UV Spectroscopy, Thin Layer Chromatography, IR Spectroscopy, 1H, 13C and dept-135 NMR. The proposed structures of the compounds were further confirmed by comparing the 13C-NMR values of the compounds with previous reported data.

Keywords


Momordica charantia, Fruit pulp juice, 1-butanol soluble part, Cucurbitane glycoside.

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Dhaka University Journal of Science ISSN 1022-2502 (Print) 2408-8528 (Online)