Three new flavonoid glycosides from the fruits of luffa echinata roxb.- a hepatoprotective plant

Abstract

Phytochemical investigation of bioactive polar extracts of Luffa echinata Roxb. fruits led to the
isolation and characterization of three new flavone glycosides viz., 3,5,7,3′,4′-pentahydroxyflavone-3-[-O-β-Dglucopyranosyl-
7-O-β-D-glucopyranoside (1),3,5,7-trihydroxy-(7′,8′- dioxo,9′,10′,-dihydro[a]cyclohex Δ13′,(14′),
Δ11′(12’)-12′,13′,-dimethyl)-flavone-7-[-O-β-D-galactopyranosyl-(1→2)]-O-β-D-glucopyranoside (2), and 5,7,8,4′-
tetrahydroxy flavone-7-[-O-β-D-xylosyl-(1→2)]-O-β-D-glucopyranoside (3). The structures of the newly isolated
compounds were elucidated on the basis of spectral data and chemical evidences.The isolated compounds are found to
be new analogs of tricetin, quercetin and isoscutellarin.