Biological Screening of Zizyphus rugosa and Zizyphus oenoplia extractives

Abstract

Different extracts of the leaves and barks of Zizyphus rugosa and Zizyphus oenoplia were studied for
their antibacterial, antifungal, and β-glucuronidase inhibitory activities. The methanol extract of Z. rugosa bark
showed significant antibacterial activity against Streptococcus pyogens, Staphylococcus aureus and Pseudomonas
aerogenes whereas the methanol extract of leaves demonstrated moderate activity against Salmonella typhi. The
chloroform and methanol extracts of Z. oenoplia showed good activity against a few bacteria strains. The chloroform
extracts of the barks and leaves of Z. rugosa also showed antifungal activity. The methanol and ethyl acetate extracts
of the bark of Z. rugosa revealed significant β-glucuronidase inhibitory activity. Lupeol, betuline, betulinaldehyde
and betulinic acid, isolated from Z. rugosa, also showed good activity against a few bacteria.