The Effect of Cast Films of Bovine Mucin and Prosopis Gum Containing a Cicatrin® Powder on Wound Healing

Abstract

The aim of this work is test the effect of cast film of bovine mucin and prosopis gum containing
cicatrin powder on wound healing in rats. Mucin was processed from the small intestine of freshly slaughtered cow
via precipitation with chilled acetone, air-drying and pulverization. Prosopis was extracted using acetone; the film
was formulated by a mixture of bovine mucin and prosopis gum. The formulations were used in the treatment of
wound inflicted on the animal and this was compared to the standard antibiotics cicatrin used in wound healing. In all
cases, there was a progressive decrease in wound area indicating an efficacy of the samples in healing. By the 15th
day, the sample containing 0.2 g of the mixture of bovine mucin, prosopis and cicatrin powder showed 100 %
healing. Th negative control show 65 %, prosopis alone showed 50 %, bovine mucine alone showed 90 % and
cicatrin alone showed 70 %. Increase in the mucin concentration gave a remarkable improvement. These results
suggest that a mixtures of bovine mucin, cicatrin and prosopis gum has a better healing effect than cicatrin powder
alone.