Toxicity of sodium fluoride (NaF) to juvenile catfish, Clarias batrachus

Abstract

Effects of sodium fluoride (NaF) on Clarias batrachus in the aquarium at a sub
lethal dose of 0, 15, 30, 40, 50 and 60 mg/l for a chronic exposure period of 120
days were evaluated. The histopathological alterations in different tissues from
brain, gill and liver were examined in fishes showed abnormal behaviors. Such
as rupture of hepatocytes, congestion, necrosis pyknosis, cellular infiltration, and
degenerative changes. In case of liver, individualization of hepetocytes, mild
necrosis, vacuolation, pyknosis and hemorrhage were observed. These results
suggest that NaF affects severely on the tissues of the internal organs leading to
threat of life and survival.