Cu(II), Zn(II), Cd(II) and Hg(II) Complexes of Pantroprazole (PPZH): Synthesis and Characterization

Abstract

Several metal complexes of pantoprazole, [Cu(PPZ)(H2O)Cl], [Zn(PPZ)2], [Cd(PPZ)2].1.5H2O and [Hg(PPZ)(H2O)Cl] have
been synthesized and characterized. Elemental analysis, IR, UV-Visible spectral analysis, magnetic measurement,
thermogravimetric analysis, differential scanning calorimetric and cyclic voltammetric techniques were used for their
characterization. The lipophilic weak base pantoprazole (PPZ) act as a potential bidentate ligand forming coordination
complexes with divalent metal ions through anionic imidazolyl N- and O atom of sulfinyl >S=O group. All complexes
possess tetrahedral geometry.