Free Radical Scavenging Activity of Andrographis paniculata and Anthocephalus chinensis

Abstract

Andrographis paniculata and Anthocephalus chinensis, the two Bangladeshi plants were studied for investigating free radical scavenging
potentiality. The crude ethanolic extract of the aerial part of Andrographis paniculata as well as its n-hexane, carbon tetrachloride,
dichloromethane and aqueous soluble fractions and the methanolic extract of the stem bark of Anthocephalus chinensis and its n-hexane, carbon
tetrachloride, chloroform and aqueous soluble fractions were subjected to this study with 2,2-Diphenyl-1-picrylhydrazyl (DPPH). The
dichloromethane soluble fraction of A. paniculata exhibits the highest free radical scavenging activity (antioxidant effect) having IC50 value of
19.33 μg/ml and the crude methanolic extract of A. chinensis showed the potential antioxidant activity having IC50 value of 22.68 μg/ml.