Scopoletin Isolated from Stem Bark of Bursera serrata Wall. With Antimicrobial and Cytotoxic Activities of the Crude Extract

Authors

  • Mohammad Habibullah
  • Al-Mansur M. A.
  • M. Mahboob Ali Siddiqi
  • A. M. Sarwaruddin Chowdhury
  • M. H. Sohrab
  • Choudhury M. Hasan

Keywords:

Bursera serrata, Burseraceae, Scopoletin, Brine shrimp lethality bioassay, antimicrobial screening.

Abstract

Scopoletin (1) was isolated from the dichloromethane soluble fraction of the Stem bark of Bursera serrata (Family:Burseraceae).The
dichloromethane extract was subjected to antimicrobial screening and brine shrimp lethality bioassay while it showed mild to poor inhibitory
activity to microbial growth and also showed significant cytotoxicity having LC50 3.1 μg/ml.

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Issue

Vol. 58 No. 2 (2010)

Section

Articles