Antioxidant Activities of Sesbania sesban and Moringa oleifera Extractives

Abstract

Extractives of two indigenous plants Sesbania sesban (Fabaceae) and Moringa oleifera (Moringaceae) were studied for evaluating
antioxidant activity. The petroleum ether, carbon tetrachloride and chloroform soluble fractions of crude methanolic extract of the leaves of
Sesbania sesban and n-hexane, carbon tetrachloride and dichloromethane soluble parts of crude methanolic extract of the stem bark of
Moringa oleifera were subjected to measure the free radical scavenging capability with 1,1-Diphenyl-2-picrylhydrazyl (DPPH). The
chloroform soluble fraction of S. sesban showed the highest free radical scavenging activity among it’s extractives having IC50 value of
17.81 μg/ml and the IC50 value of aqueous soluble part was found 21.72 μg/ml. On the other hand, dichloromethane soluble fraction of M.
oleifera exhibits the highest antioxidant (free radical scavenging) activity having IC50 value of 27.49 μg/ml. and the IC50 value of carbon
tetrachloride soluble part was 35.78 μg/ml.