Slope of V–t curves of Evoked Muscle Potentials for Diagnosis of Neural Disorders

Abstract

A nerve trunk consists of many individual nerve fibers with a specific Distribution of Conduction Velocity (DCV), which may change
with neural disorders. A technique was earlier presented in which the time distribution of voltage amplitude deviation (V–t) of
evoked muscle responses from two conduction distances was used to extract qualitative information on DCV. This was shown to have
some degree of success using simulated compound muscle action potentials for various assumed gross disorders of DCV. In the
present work slopes of the earlier V–t curves from simulated potentials, and their ratios were used to identify patterns that may
provide further indications of the disorders, increasing confidence in the diagnosis.